Are you a beginning podcaster on a budget? If you need a place to host your large audio files, give Switchpod a try. What do they have to offer? They have a free plan with 450MB of storage, a $5/month plan with 500MB, a $10/month plan with 1GB, and a $30/month plan with 2GB of storage. For more experienced podcasters, LibSyn is probably a better deal, but for beginners, you can’t beat Switchpod.
Though they offer to create a website for your podcast, I prefer to do that myself with good-old WordPress.